gene 759 words KG: MYC 2026-03-24
kind:genesection:genesstate:published
Contents

MYC Gene

🧬 Gene Info
Gene SymbolMYC
Chromosome8q24.21
Functionis an important component in the neurobiology of neurodegenerative diseases.
Exons3
PathwaysAkt, Amyloid, Angiogenesis, Apoptosis, Autophagy
Ensembl IDENSG00000136997
GeneCardsMYC
Human Protein AtlasMYC
Associated DiseasesALS, Aging, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
Known Drugs/CompoundsZuojin Pill, RAPAMYCIN, LWDHD, MYC inhibitors, Bazhen Decoction, COENZYME Q10
InteractionsEGFR, MMP9, BCL2, PINK1, STAT3, PI3K
KG Connections2117 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (30)

ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.66
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.47
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Transcriptional Autophagy-Lysosome Coupling
Score: 0.66

Related Analyses (5)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

PDGFRA and C-MYC protein validation in ovarian cancer tissue
exploratory · proposed · Score: 0.85
Neural Stem Cell Therapy for Alzheimer's Disease
clinical · proposed · Score: 0.40

See Also (11)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
AKT3 Gene
gene · KG edge: therapeutic_target
AKT1 Gene
gene · KG edge: activates
AIF Gene
gene · KG edge: regulates
ADRB2 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

MYC mediates CAR T CELL EXPANSION
MYC activates CAR T CELL PROLIFERATION
MYC activates PIK3C3
MYC activates PPARA
MYC activates PPARGC1A
MYC activates RAB7A
MYC activates RPS6
MYC activates RPS6KB1
MYC activates RUBCN
MYC activates SREBF1