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gene 759 words KG: MYC
Contents

MYC Gene

🧬 Gene Info
Gene SymbolMYC
Chromosome8q24.21
Functionis an important component in the neurobiology of neurodegenerative diseases.
Exons3
PathwaysAkt, Amyloid, Angiogenesis, Apoptosis, Autophagy
Ensembl IDENSG00000136997
GeneCardsMYC
Human Protein AtlasMYC
Associated DiseasesAging, Als, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
Known Drugs/CompoundsBazhen Decoction, COENZYME Q10, LWDHD, MYC inhibitors, rapamycin, RAPAMYCIN
Interactions66CTG peptide, ABCD1, ABCD2, ABL1, ACETYL-COA, ACHE
KG Connections2148 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (44)

ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.89Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.83Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79Competitive APOE4 Domain Stabilization Peptides
Score: 0.78Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.78Transcriptional Autophagy-Lysosome Coupling
Score: 0.78Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.77CYP46A1 Overexpression Gene Therapy
Score: 0.77APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76Circadian Clock-Autophagy Synchronization
Score: 0.76Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75APOE Isoform Expression Across Glial Subtypes
Score: 0.74Epigenetic Memory Erasure via TET2 Activation
Score: 0.74PARP1 Inhibition Therapy
Score: 0.74Phase-Separated Organelle Targeting
Score: 0.73Metabolic Switch Targeting for A1→A2 Repolarization
Score: 0.73TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
pg 1/3Next →

Related Analyses (5)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedMitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedEpigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

PDGFRA and C-MYC protein validation in ovarian cancer tissue
exploratory · proposed · Score: 0.85Neural Stem Cell Therapy for Alzheimer's Disease
clinical · proposed · Score: 0.40

See Also (11)

ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: therapeutic_targetABCD1 — ATP Binding Cassette Subfamily D Member 1
gene · KG edge: activatesABCD2 — ATP Binding Cassette Subfamily D Member 2
gene · KG edge: activatesACSL4 Gene - Acyl-CoA Synthetase Long Chain Family Memb
gene · KG edge: regulatesACTB Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

STAT3 regulates MYC
ACTB regulates MYC
PPARA regulates MYC
CAT regulates MYC
SQSTM1 regulates MYC
RPS6KB1 regulates MYC
RAB7A regulates MYC
SREBF1 regulates MYC
EIF4EBP1 regulates MYC
CTSD regulates MYC

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