protein 1,532 words KG: 1433PROTEIN
Contents

14-3-3 Proteins — Adapter and Scaffold Proteins

🔬 Protein Info
Gene Symbol1433PROTEIN
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionmotor neurons and may contribute to selective vulnerability - TDP-43 pathology: 14-3-3 proteins interact with TDP-43 and may influence its aggrega
Subcellular Localization5. **Transcriptional regulation**: Interact with transcription factors
Molecular Weight28 kDa
Amphipathic groovebinds phosphorylated serine/threonine motifs
N-terminal dimerization domainforms functional dimers
C-terminal regulatory tailmodulates interactions
Associated Diseasesneurodegeneration
KG Connections1 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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