gene 2,588 words KG: ABCA7
Contents

ABCA7 (ATP-Binding Cassette Transporter A7)

🧬 Gene Info
Gene SymbolABCA7
FunctionABCA7 encodes ATP-binding cassette transporter A7, a member of the ABC transporter family.
Primary Expressionimmune cells and the brain, where it plays important roles in lipid transport and cellular homeostasis
PathwaysCholesterol, Glycolysis, Immune Response, Lipid Metabolism, Nf-Κb
Ensembl IDENSG00000064687
GeneCardsABCA7
Human Protein AtlasABCA7
Lipid effluxMediates transport of lipids to apolipoproteins
Phospholipid transportTransfers phospholipids across cellular membranes
Cholesterol homeostasisRegulates cellular cholesterol levels
Immune functionModulates macrophage and microglial responses
PhagocytosisInvolved in cellular clearance mechanisms
Associated DiseasesALZHEIMER'S DISEASE, Als, Alzheimer, Atherosclerosis
InteractionsNPY, CASS4, EPHA1, CLU, BIN1, CD33
KG Connections591 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph