| Gene Symbol | AHSA1 |
| Aliases | AHSA1PROTEIN |
| Protein Type | Chaperone |
| Function | AHSA1 (Activator of Hsp90 ATPase 1), also known as Hsp90 co-chaperone AHA1, is a key co-chaperone that stimulates the ATPase activity of Hsp90. |
| Primary Expression | Purkinje cells |
| Molecular Weight | 38 kDa |
| Amino Acids | 338 aa |
| Ensembl ID | ENSG00000100526 |
| GeneCards | AHSA1 |
| Human Protein Atlas | AHSA1 |
| N-terminal domain | Binds to Hsp90 and stimulates its ATPase activity |
| C-terminal domain | Contains the catalytic center for ATP hydrolysis stimulation |
| ATPase stimulation | Accelerates Hsp90 ATP hydrolysis 10-fold |
| Client protein maturation | Facilitates folding of Hsp90 client proteins |
| Protein quality control | Helps prevent aggregation of misfolded proteins |
| Associated Diseases | Alzheimer's Disease |
| Interactions | EGFR, HSP90AA1, TGFB1 |
| KG Connections | 6 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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