biomarker 1,084 words KG: ent-gene-b844ed8e 2026-03-24
kind:biomarkersection:biomarkersstate:published
Contents

Fibroblast Growth Factor 21 (FGF21)

🔬 Protein Info
Gene SymbolFGF21
Full NameFibroblast Growth Factor 21
Chromosome12q13
Functionencodes a member of the FGF19 subfamily of fibroblast growth factors that functions primarily as a metabolic regulator.
Molecular Weight22.5 kDa
Amino Acids209 aa
PathwaysApoptosis, Autophagy, Mtor
UniProt IDQ9NS73
NCBI Gene ID26291
Ensembl IDENSG00000163410
OMIM609436
GeneCardsFGF21
Human Protein AtlasFGF21
CategoryMetabolic Biomarker
TargetFGF21 protein
Associated DiseasesAging, Als, Alzheimer, Amyotrophic Lateral Sclerosis Survival, Diabetes, Fibrosis
Known Drugs/Compoundsmetformin
InteractionsULK1, KDM6B, LC3, ATG7, FNDC5, PLAU
KG Connections504 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph