| Gene Symbol | MTNR1A |
| Protein Type | Gpcr |
| Target Class | Gpcr |
| Function | Small molecule agonists that activate G-protein coupled receptor signaling |
| Mechanism of Action | Small molecule agonists that activate G-protein coupled receptor signaling |
| Druggability | Medium (0.57) |
| Clinical Stage | Approved |
| Pathways | Circadian rhythm / glymphatic clearance, Early neurodevelopment, LRP1 receptor-mediated transcytosis |
| UniProt ID | Q8WZ72 |
| GeneCards | MTNR1A |
| Human Protein Atlas | MTNR1A |
| Taxonomy | ID |
| Cell Ontology (CL) | CL:0000197 |
| Associated Diseases | ALS, ALZHEIMER, AUTISM, Alzheimer's disease |
| Known Drugs/Compounds | NG-497, linalool |
| Interactions | LRP1, MTNR1B, NPAS2, PER1, PER2, CNR2 |
| SciDEX Target | View Target Profile (8 clinical trials) |
| SciDEX Hypotheses | Circadian Glymphatic Rescue Therapy (Melatonin-foc |
| KG Connections | 351 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |