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disease 1,185 words KG: ent-dise-176b17e8
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Autism Spectrum Disorder

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OMIMMeSHWikipedia

Related Hypotheses (16)

Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78Complement C1q Mimetic Decoy Therapy
Score: 0.69Microbial Inflammasome Priming Prevention
Score: 0.65APOE-Dependent Autophagy Restoration
Score: 0.89Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76APOE-TREM2 Interaction Modulation
Score: 0.74Lysosomal Enzyme Trafficking Correction
Score: 0.71Lysosomal Calcium Channel Modulation Therapy
Score: 0.70Lysosomal Positioning Dynamics Modulation
Score: 0.69TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67TREM2-Dependent Microglial Senescence Transition
Score: 0.62TREM2-mediated microglial tau clearance enhancement
Score: 0.62TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58Lysosomal Membrane Repair Enhancement
Score: 0.54

Related Analyses (7)

Synaptic pruning by microglia in early AD
neurodegeneration · archivedMechanistic role of APOE in neurodegeneration
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archivedAutophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archivedMetabolic reprogramming in neurodegenerative disease
neurodegeneration · completed

Related Experiments (9)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40Cytochrome Therapeutics
clinical · proposed · Score: 0.40iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · completed · Score: 0.90RBG treatment in ApoE-/- atherosclerosis mouse model
validation · proposed · Score: 0.90Leukocyte gene expression analysis in COVID-19 patients
exploratory · proposed · Score: 0.90

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