| PARK19 | Numerical designation in the PARK gene nomenclature system |
| DNAJC6 | DnaJ heat shock protein family (Hsp40) member C6 |
| Auxilin-2 | Originally named for its similarity to auxilin-1 (DNAJC5), involved in synaptic vesicle recycling |
| European descent | ~1 in 500-1,000 |
| East Asian | ~1 in 1,000-2,000 |
| Middle Eastern | Higher due to consanguinity 7 8 |
| Early onset | Typically before age 30, often in adolescence or early adulthood |
| Rapid progression | Early development of motor complications compared to idiopathic PD |
| Good levodopa response | Patients respond well to dopaminergic therapy |
| Typical PD signs | Resting tremor, bradykinesia, rigidity, postural instability |
| Parkinsonism asymmetry | Often begins asymmetrically 9 |
| Databases | OMIMOrphanetClinicalTrialsPubMed |