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Spinal Amyotrophic Lateral Sclerosis

Disease Info

Prevalence	4-6 per 100,000 population
Incidence	1-2 per 100,000 annually
Age of onset	Typically 55-60 years (younger than bulbar onset)
Gender distribution	Male predominance (1.5-2:1)
Geographic variation	Higher incidence in some populations (e.g., Guam, Kii Peninsula)
Databases	OMIM Orphanet ClinicalTrials PubMed

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