| Gene Symbol | DLG1 |
| Full Name | Discs Large Homolog 1 |
| Aliases | MAGUK Scaffold |
| Chromosome | 3q29 |
| Protein Type | Scaffold Protein |
| Function | DLG1/MAGUK scaffold protein functions in: - Synaptic organization: Forms core of postsynaptic density - NMDA receptor anchoring: Recruits NMDA and AMPA receptors to synapses - Synaptic plasticity: Ess |
| Primary Expression | excitatory glutamatergic neurons, particularly in pyramidal neurons of layers 2/3 and 5 of the cerebral cortex |
| Molecular Weight | 102 kDa |
| Amino Acids | 922 aa |
| UniProt ID | Q12959 |
| NCBI Gene ID | 1739 |
| Ensembl ID | ENSG00000075711 |
| OMIM | 601014 |
| GeneCards | DLG1 |
| Human Protein Atlas | DLG1 |
| Associated Diseases | neurodegeneration |
| Interactions | GJA1 |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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