| Gene Symbol | ANO7 |
| Full Name | Anoctamin 7 |
| Aliases | Anoctamin 7 (TMEM16G |
| Chromosome | 7p21.3 |
| Protein Family | Anoctamin/TMEM16 |
| Protein Type | Channel |
| Function | ANO7 encodes a calcium-activated chloride channel (CaCC) with the following characteristics |
| Primary Expression | the brain and testis, with highest expression in the hippocampus and cerebral cortex |
| GeneCards | ANO7 |
| Human Protein Atlas | ANO7 |
| Calcium activation | Intracellular calcium binding triggers channel opening [@tian2012] |
| Brain expression | High levels in hippocampus (CA1-CA3), cerebral cortex, and cerebellum [@framework] |
| Cellular localization | Primarily plasma membrane, with some intracellular pools [@pedemonte2014] |
| Ion selectivity | Selective for chloride over other anions [@yang2008] |
| Alzheimer's Disease | Altered expression patterns observed in AD brain tissue [@hansen2014] |
| Associated Diseases | Neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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