gene 2,185 words KG: ASTN1 2026-03-28
kind:genesection:genesstate:publishedtopic:neuronal-migrationtopic:synaptic-adhesiontopic:cortical-developmenttopic:autismtopic:intellectual-disabilitytopic:brain-development
Contents

ASTN1 Gene

🧬 Gene Info
Gene SymbolASTN1
Full NameAstrotactin 1
Chromosome1q25.1
Protein TypeReceptor
Functionencodes a neuronal membrane protein that functions as a critical receptor mediating glial-guided neuronal migration during brain development.
Primary Expressionmature neurons where it contributes to synaptic plasticity and stability[@sudhof2022][@barrow2021]
Molecular Weight175 kDa
Amino Acids555 aa
Exons30
UniProt IDQ9UPW0
NCBI Gene ID460
Ensembl IDENSG00000112282
OMIM607385
GeneCardsASTN1
Human Protein AtlasASTN1
Associated DiseasesAutism
DatabasesGeneCardsHPASTRING

Knowledge Graph