| Gene Symbol | CTSE |
| Full Name | Cathepsin E |
| Chromosome | 1q31.3 |
| Protein Type | Protease |
| Function | is a gene located on chromosome 1q31. |
| Subcellular Localization | endosomal compartments and the trans-Golgi network rather than in lysosomes. This subcellular distribution suggests dist |
| Amino Acids | 426 aa |
| UniProt ID | [P10111](https://www.uniprot.org/uniprot/P10111) |
| Ensembl ID | ENSG00000105638 |
| GeneCards | CTSE |
| Human Protein Atlas | CTSE |
| Immune cells | Highest expression in macrophages, monocytes, and dendritic cells |
| Gastrointestinal tract | Abundant in gastric mucosa and intestinal epithelium |
| Brain | Low to moderate expression in neurons, microglia, and astrocytes |
| Microglial activation | Cathepsin E in microglia contributes to the inflammatory cascade by regulating cytokine production and inflammasome activation |
| Associated Diseases | neurodegeneration |
| KG Connections | 4 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |