gene 1,464 words KG: DYNC1LI2 2026-03-27
kind:genesection:genesstate:publishedtopic:alzheimerstopic:parkinsonspathway:axonal-transportpathway:cytoskeletal-transport
Contents

DYNC1LI2 Gene

🧬 Gene Info
Gene SymbolDYNC1LI2
Full NameDynein Cytoplasmic 1 Light Intermediate Chain 2
Chromosome15q21.3
Functionencodes a critical component of the cytoplasmic dynein-1 complex, the primary motor responsible for retrograde axonal transport in neurons.
Molecular Weight50 kDa
Amino Acids523 aa
Ensembl IDENSG00000170840
GeneCardsDYNC1LI2
Human Protein AtlasDYNC1LI2
NucleusPositioning in cell body
Golgi apparatusPerinuclear localization
LysosomesClustering near centrosome
EndosomesVesicular distribution
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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