gene 3,390 words KG: EPHA7 2026-03-25
kind:genesection:genesstate:published
Contents

EPHA7 Gene

🧬 Gene Info
Gene SymbolEPHA7
Full NameEphrin Type-A Receptor 7
Chromosome6q16.1
Protein TypeReceptor
FunctionNeuronal Migration: During cortical development, EPHA7 guides migrating neurons to their correct positions in the developing cortex[@wang2018].
Primary ExpressionNeurons, Astrocytes, Oligodendrocyte precursors
Molecular Weight110 kDa
Amino Acids983 aa
Exons17
UniProt IDQ9Y232
NCBI Gene ID2845
Ensembl IDENSG00000126890
OMIM602088
GeneCardsEPHA7
Human Protein AtlasEPHA7
Associated DiseasesAlzheimer's Disease, Parkinson's Disease, Cancer (tumor suppressor)
KG Connections1 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (21)

Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
TREM2-Dependent Microglial Senescence Transition
Score: 0.69
CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (1 edges)

TCF/LEF binds EPHA7