gene 1,790 words KG: GID4
Contents

GID4 Gene

🧬 Gene Info
Gene SymbolGID4
Full NameGLUT4 Degradation Protein
Chromosome17p13.1
Protein TypeLigase
Functionencodes a critical subunit of the GID (Glucose-Induced Degradation) ubiquitin ligase complex.
Primary Expressionvarious brain cell types:
Molecular Weight38 kDa
Amino Acids345 aa
Exons12
UniProt ID[Q9H7M0](https://www.uniprot.org/uniprot/Q9H7M0)
Ensembl IDENSG00000131023
OMIM618002
GeneCardsGID4
Human Protein AtlasGID4
N-terminal domainProline/glutamine-rich region involved in substrate recognition
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

APOE-Dependent Autophagy Restoration
Score: 0.89
CYP46A1 Overexpression Gene Therapy
Score: 0.77
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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