gene 2,976 words KG: GPR161 2026-03-27
kind:genesection:genesstate:published
Contents

GPR161 — G Protein-Coupled Receptor 161

🧬 Gene Info
Gene SymbolGPR161
Full NameG protein-coupled receptor 161
Chromosome1q24.2
Functionis a GPCR involved in Hedgehog signaling and neural tube development.
Molecular Weight~77 kDa
Amino Acids713 aa
Exons12
UniProt IDQ9Y4X5
NCBI Gene ID266977
Ensembl IDENSG00000135547
GeneCardsGPR161
Human Protein AtlasGPR161
Protein NameGPR161
Protein Size713 amino acids
Genomic Size~15 kb
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (15)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
APOE-Dependent Autophagy Restoration
Score: 0.61
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52

Related Analyses (8)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in