gene 1,688 words KG: GTF2H2 2026-03-29
section:geneskind:genetopic:alzheimerstopic:parkinsons
Contents

GTF2H2 Gene

🧬 Gene Info
Gene SymbolGTF2H2
AliasesBTF2p44, TFB2, p44
Chromosome5q13.2
Functionis a component of the XPB (ERCC3)-containing core TFIIH subcomplex.
Primary ExpressionUbiquitous; high in brain, testis, thymus
Molecular Weight~44 kDa
Amino Acids395 aa
UniProt IDQ13887
NCBI Gene ID2966
GeneCardsGTF2H2
Human Protein AtlasGTF2H2
Protein Length395 amino acids
Protein ClassGeneral transcription factor, DNA repair protein
XPB (ERCC3)Direct binding
GTF2H3Heterodimerization
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsHPASTRING

Knowledge Graph