| Gene Symbol | HERC1 |
| Full Name | HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase 1 |
| Chromosome | 15q22.31 |
| Protein Type | Ligase |
| Function | is a massive E3 ubiquitin ligase enzyme that plays critical roles in protein quality control, autophagy, DNA repair, and cellular signaling. |
| Subcellular Localization | 2. **HECT Domain** (C-terminal) |
| Molecular Weight | 532 kDa |
| Amino Acids | 862 aa |
| Exons | 54 |
| Pathways | HERC1 Role |
| Ensembl ID | ENSG00000102786 |
| GeneCards | HERC1 |
| Human Protein Atlas | HERC1 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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