| Gene Symbol | LHX2 |
| Full Name | LIM Homeobox 2 |
| Chromosome | 9q31.3 |
| Protein Type | Gene |
| Function | is a LIM-type homeobox transcription factor that plays critical roles in the development and maintenance of the nervous system. |
| Subcellular Localization | The LIM domains contain zinc-finger motifs that coordinate zinc ions, creating a stable protein fold |
| Molecular Weight | 45 kDa |
| Amino Acids | 406 aa |
| GeneCards | LHX2 |
| Human Protein Atlas | LHX2 |
| Linker region | Connects the LIM domains to the homeodomain, contains regulatory sequences |
| Ldb1/Ldb2 | Co-factors that form complexes with LIM proteins |
| Clim/NLI | Nuclear co-factors that enhance transcriptional activity |
| RORβ | Nuclear receptor involved in cortical development |
| Bmp signaling molecules | Regulates LHX2 expression in developing cortex |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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