gene 988 words KG: NIPA1 2026-03-24
kind:genesection:genesstate:published
Contents

NIPA1 Gene

🧬 Gene Info
Gene SymbolNIPA1
Full NameNon-imprinted in Prader-Willi/Angelman Syndrome 1
Chromosome9q21.13
Protein TypeTransporter
Functionencodes a magnesium transporter protein that plays critical roles in neuronal function, synaptic transmission, and intracellular magnesium homeostasis.
Amino Acids317 aa
UniProt ID[Q9BUE2](https://www.uniprot.org/uniprot/Q9BUE2)
Ensembl IDENSG00000139970
GeneCardsNIPA1
Human Protein AtlasNIPA1
Ion SpecificityHighly selective for magnesium over other divalent cations
Transport MechanismElectrogenic Mg²⁺/H⁺ antiport mechanism
pH SensitivityActivity modulated by intracellular pH
RegulationControlled by cellular magnesium status and neuronal activity
Associated Diseasesneurodegeneration
KG Connections3 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph