gene 1,138 words KG: NOG
Contents

NOG Gene

🧬 Gene Info
Gene SymbolNOG
Full NameNoggin
Chromosome17q22
Functionencodes a secreted polypeptide that functions as a potent BMP antagonist.
Primary Expressionthe adult brain, where it modulates synaptic plasticity and neuronal survival
Amino Acids232 aa
Exons3
UniProt IDQ15070
NCBI Gene ID9241
Ensembl IDENSG00000183611
GeneCardsNOG
Human Protein AtlasNOG
Signal peptideN-terminal secretion signal (24 amino acids)
Noggin domainCentral region mediating BMP binding
Cysteine-rich regionForms disulfide bonds for stability
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsHPASTRING

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