gene 1,594 words KG: PLPPR1 2026-03-28
kind:genesection:genesstate:publishedtopic:parkinsonstopic:alzheimers
Contents

PLPPR1 Gene

🧬 Gene Info
Gene SymbolPLPPR1
Full NamePhospholipid Phosphatase-Related Protein 1
Chromosome9p13.3
Protein TypePhosphatase
Functionis a member of the lipid phosphate phosphatase (LPP) family within the broader family of phosphatidic acid phosphatases (PAPs).
Amino Acids50 aa
UniProt ID[Q9Y329](https://www.uniprot.org/uniprot/Q9Y329)
Ensembl IDENSG00000143125
GeneCardsPLPPR1
Human Protein AtlasPLPPR1
LPA regulationDephosphorylates LPA to monoacylglycerol (MAG), terminating LPA signaling
S1P regulationModulates S1P levels, affecting cell survival and migration
Spatial signalingShapes lipid gradients important for cell-cell communication
Associated DiseasesParkinson's disease, Alzheimer's disease
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph