Contents

RGS10 Gene

🧬 Gene Info

Gene Symbol	RGS10
Full Name	Regulator of G Protein Signaling 10
Chromosome	10q26.11
Function	encodes a member of the RGS family of GTPase-activating proteins that negatively regulate G protein-coupled receptor (GPCR) signaling.
Primary Expression	both neuronal and glial populations [7]:
Subcellular Localization	and function. The RGS domain adopts a characteristic alpha-helical bundle structure that mediates binding to active Gα s
Amino Acids	180 aa
UniProt ID	Q9NS28
NCBI Gene ID	6004
Ensembl ID	ENSG00000148991
OMIM	602866
GeneCards	RGS10
Human Protein Atlas	RGS10
Cerebral Cortex	Moderate to high expression in cortical layers, particularly layer V pyramidal neurons
Hippocampus	High expression in CA1-CA3 pyramidal neurons and dentate gyrus granule cells
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

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