gene 1,225 words KG: RICTORV2 2026-03-22
kind:genesection:genesstate:published
Contents

RICTOR Gene

🧬 Gene Info
Gene SymbolRICTOR
Full NameRaptor Independent Companion of mTOR
AliasesRaptor Companion
Chromosome5p13.1
Protein TypemTOR Complex Component
Functionencodes a critical component of the mechanistic target of rapamycin complex 2 (mTORC2), a key signaling hub that regulates cell survival, metabolism, cytoskeletal organization, and synaptic plastic...
Molecular Weight200 kDa
Amino Acids708 aa
PathwaysmTOR, mtor, mTOR signaling, MAPK
UniProt IDQ6R327
NCBI Gene ID253782
Ensembl IDENSG00000164327
OMIM610027
GeneCardsRICTOR
Human Protein AtlasRICTOR
Associated Diseasesneurodegeneration
Known Drugs/Compoundsrapamycin
InteractionsMTOR, PIK3C3, EGFR, PPARG, HSPA5, MAVS
KG Connections424 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (16)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (2 edges)

RICTORV2 data_in benchmark_ot_ad_answer_key:RICTORV2
benchmark_ot_ad_answer_key:RICTORV2 data_in RICTORV2