| Gene Symbol | RPS15 |
| Chromosome | 19p13.2 |
| Function | mRNA decoding: The decoding center where codon-anticodon pairing is verified |
| Molecular Weight | 17.2 kDa |
| Amino Acids | 145 aa |
| Ensembl ID | ENSG00000149091 |
| GeneCards | RPS15 |
| Human Protein Atlas | RPS15 |
| RNA-binding domain | Facilitates codon-anticodon base pairing |
| RPS19-binding site | Forms heterodimer with RPS19 for ribosome assembly |
| Nucleolar localization signal | Targets protein to nucleolus for ribosome biogenesis |
| Somatic mutations | RPS15 mutations identified in sporadic ALS motor neurons |
| Ribosomal dysfunction | Global translation impairment in ALS |
| Nucleolar stress | Nucleolar alterations in ALS postmortem tissue |
| p53 activation | Ribosomal stress may contribute to p53-dependent cell death |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |