gene 1,489 words KG: RPS21
Contents

RPS21 — Ribosomal Protein S21

🧬 Gene Info
Gene SymbolRPS21
Full NameRibosomal Protein S21
Chromosome21q22.3
Primary Expressionneurons, astrocytes, and microglia, where it supports the high protein synthesis demands required for synaptic function, axonal transport, and cellula
Molecular Weight9.1 kDa
Amino Acids83 aa
Exons3
PathwaysMAPK
UniProt IDP63220
NCBI Gene ID6157
GeneCardsRPS21
Human Protein AtlasRPS21
Associated Diseasesneurodegeneration
KG Connections8 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

APOE-Dependent Autophagy Restoration
Score: 0.89
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Nucleolar Stress Response Normalization
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (3)

Neurodegeneration
disease · KG edge: implicated_in
GPX4 Gene - Glutathione Peroxidase 4
gene · KG edge: stabilizes
MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: regulates

Knowledge Graph (8 edges)

RPS21 inhibits cell proliferation
RPS21 inhibits cell migration
RPS21 inhibits cell invasion
RPS21 participates_in EIF-2 signaling pathway
RPS21 stabilizes GPX4
RPS21 regulates MAPK
RPS21 participates_in 18S rRNA maturation
RPS21 participates_in 40S ribosomal subunit formation

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