gene 3,223 words KG: TBX2 2026-03-25
kind:genesection:genesstate:publishedtopic:alzheimerstopic:parkinsons
Contents

TBX2 — T-Box Transcription Factor 2

🧬 Gene Info
Gene SymbolTBX2
Full NameT-Box Transcription Factor 2
Chromosome17q23.2
Protein TypeTranscription Factor
Functionis a member of the T-box family of transcription factors that play critical roles in embryonic development, tissue patterning, and cellular differentiation.
Primary Expressionthe developing and adult brain, where it regulates genes involved in neuronal differentiation, survival, and function
Subcellular Localization**Sumoylation**: Sumoylation of TBX2 may modulate its repressive functions
Molecular Weight~75 kDa
Amino Acids680 aa
Exons8
UniProt IDQ9URJ3
NCBI Gene ID6903
GeneCardsTBX2
Human Protein AtlasTBX2
Protein ClassTranscription Factor
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsHPASTRING

Knowledge Graph