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gene 652 words KG: TFEC
Contents

TFEC Gene

🧬 Gene Info
Gene SymbolTFEC
Full NameTranscription Factor EC
Chromosome6p21.1
Protein FamilybHLH-Zip (MITF/TFEB/TFE3/TFEC)
FunctionLysosomal biogenesis, autophagy regulation
Primary ExpressionMicroglia, brain macrophages
Pathwayspathway: ```mermaid, mTOR
GeneCardsTFEC
Human Protein AtlasTFEC
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (18)

TREM2-Dependent Microglial Senescence Transition
Score: 0.95CYP46A1 Overexpression Gene Therapy
Score: 0.89APOE-Dependent Autophagy Restoration
Score: 0.85TREM2-mediated microglial tau clearance enhancement
Score: 0.80Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.78

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedSynaptic pruning by microglia in early AD
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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