gene 2,432 words KG: TREM3
Contents

Triggering Receptor Expressed on Myeloid Cells 3 (TREM3)

🧬 Gene Info
Gene SymbolTREM3
Full NameTriggering Receptor Expressed on Myeloid Cells 3
Chromosome6p21.1
Protein FamilyTREM family (Immunoglobulin superfamily)
Protein TypeReceptor
Functionis a member of the TREM family of immunoreceptors that play critical roles in innate immune signaling.
Primary Expressioncells of myeloid lineage:
Molecular Weight12 kDa
Gene TypeProtein coding
UniProt IDQ9NYC5
NCBI Gene ID54206
Ensembl IDENSG00000177453
OMIM605538
GeneCardsTREM3
Human Protein AtlasTREM3
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (22)

TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48
← Prevpg 2/2

Related Analyses (7)

Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived

Related Experiments (14)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Exosomal miR-155 in Neurodegeneration
biomarker · Pages share 3 hypotheses
Synaptic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses
Liquid Biopsy in Neurodegeneration
biomarker · Pages share 3 hypotheses
Metabolomic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

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