Contents

UNC5D

🧬 Gene Info

Gene Symbol	UNC5D
Full Name	UNC-5 Netrin Receptor D
Chromosome	8p23.1
Protein Type	Receptor
Function	is a type I transmembrane receptor composed of multiple functional domains that mediate ligand binding, downstream signaling, and interactions with adaptor proteins.
Primary Expression	Brain (cortex, cerebellum), embryonic
UniProt ID	[Q6ZNG7](https://www.uniprot.org/uniprot/Q6ZNG7)
GeneCards	UNC5D
Human Protein Atlas	UNC5D
Death domain (DD)	Triggers caspase-dependent apoptosis when the receptor is unbound to ligand
ZU-5 domain	Mediates protein-protein interactions with downstream effectors
PXXP motifs	Bind SH3 domain-containing adaptor proteins including TRAF6 and NCK
Associated Diseases	neurodegeneration
KG Connections	4 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Knowledge Graph