mechanism_cluster 215 words
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RNA Processing, Splicing, and RNP Granules Consensus

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Related Hypotheses (98)

RBM45 Liquid-Liquid Phase Separation Dominance Hijacks RNA P
Score: 0.87
Gamma Oscillation Entrainment Enhances lncRNA-9969-Mediated
Score: 0.87
SFPQ Paralog Displacement Triggers Cryptic Polyadenylation a
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hnRNP A2/B1 Staufen2-Mediated Axonal RNA Granule Transport F
Score: 0.85
TDP-43 RNA-proteostasis failure across ALS, FTD, and AD/LATE
Score: 0.83
GLE1-Mediated mRNA Export Defect Creates Translation-Compete
Score: 0.82
MATR3 Nuclear Body Disruption Impairs RNA Processing Hubs an
Score: 0.80
Vicious Cycle Hypothesis: Cholinergic Dysfunction Exacerbate
Score: 0.79
Stress-granule RNA-binding protein phase transition across A
Score: 0.78
METTL3-Mediated m6A Modification of lncRNA-0021 Regulates mi
Score: 0.77
Direct Toxicity Hypothesis: β-Amyloid Directly Impairs Choli
Score: 0.77
Seed-Proximal Asymmetric Duplex Stability Confers lncRNA-002
Score: 0.73
m6A RNA Modification as Address Code for Granule Targeting
Score: 0.70
C9orf72 repeat RNA and dipeptide-repeat toxicity in ALS/FTD
Score: 0.70
Axonal RNA Transport Reconstitution
Score: 0.70
hnRNPA2B1-Mediated Structural Remodeling Controls lncRNA-002
Score: 0.68
FUS Phase Separation Dominance in FTD-TDP: Aberrant Condensa
Score: 0.68
Seed match plus local RNA structure jointly determine lncRNA
Score: 0.67
Enhancing Vagal Cholinergic Signaling to Restore Gut-Brain A
Score: 0.67
m6A Hypermethylation of SNCA mRNA Stabilises Alpha-Synuclein
Score: 0.66
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Knowledge Graph (8 edges)

NPM1 associated_with RNA
APOE associated_with RNA
RNA associated_with SIRT1
HDAC associated_with RNA
RNA_POLYMERASE participates_in PROTEIN_COMPLEXES
RBP regulates mRNA_SPLICE
RBP regulates mRNA_TRANSL
RBP regulates mRNA_STAB

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