| Gene Symbol | NPM1 |
| Aliases | Nucleophosmin |
| Chromosome | 5q35.1 |
| Protein Type | Chaperone |
| Target Class | Chaperone |
| Function | Small molecule modulators of nucleolar function and protein interactions |
| Mechanism of Action | Small molecule modulators of nucleolar function and protein interactions |
| Druggability | Low (0.30) |
| Clinical Stage | Phase III |
| Molecular Weight | 37 kDa |
| Amino Acids | 294 aa |
| Exons | 12 |
| Pathways | Apoptosis |
| UniProt ID | A0A7I2V5J8 |
| Ensembl ID | ENSG00000126016 |
| GeneCards | NPM1 |
| Human Protein Atlas | NPM1 |
| Associated Diseases | ALS, Acute Myeloid Leukemia, Cancer, Carcinoma, Cardiac |
| Known Drugs/Compounds | NSC348884 |
| Interactions | NLRC5, CD8, IRF1, CIITA, G3BP1, XPO1 |
| SciDEX Target | View Target Profile (10 clinical trials) |
| SciDEX Hypotheses | Nucleolar Stress Response Normalization |
| KG Connections | 315 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |