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mechanism 3,282 words KG: synaptic_dysfunction
Contents

Synaptic Dysfunction Pathway

⚙ Mechanism Info
Namesynaptic_dysfunction
Key Genes/ProteinsC1Q, protein_oligomers
Related Diseasesearly_AD, neurodegeneration
Related Pathwaysneuroinflammation
Linked Hypotheses1 hypotheses

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🌐 Cross-references

Wikipedia

Related Hypotheses (43)

APOE-Mediated Synaptic Lipid Raft Stabilization
Score: 0.65Complement-Mediated Synaptic Pruning Dysregulation
Score: 0.61Brain Insulin Resistance with Glucose Transporter Dysfunctio
Score: 0.60
← Prevpg 3/3

Related Analyses (30)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archivedSenolytic therapy for age-related neurodegeneration
neurodegeneration · archivedSynaptic pruning by microglia in early AD
neurodegeneration · archivedNeuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedEpigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (3)

CA2 Pyramidal Neurons
cell · KG edge: causesNeurodegeneration
disease · KG edge: contributes_toC3 — Complement Component 3
gene · KG edge: causes

Knowledge Graph (5 edges)

protein_oligomers causes synaptic_dysfunction
synaptic_dysfunction contributes_to neurodegeneration
C1Q causes synaptic_dysfunction
synaptic_dysfunction biomarker_for early_AD
neuroinflammation causes synaptic_dysfunction

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