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Protein: AQP4 Protein — Aquaporin 4
protein
766 words
KG: AQUAPORIN4
2026-03-22
kind:protein
section:proteins
state:published
Contents
AQP4 Protein — Aquaporin 4
🔬
Protein Info
Gene Symbol
AQUAPORIN4
Aliases
AQUAPORIN4
Subcellular Localization
</strong></td><td>Astrocyte end-feet, perivascular, ependymal</td></tr>
Databases
GeneCards
UniProt
NCBI Gene
HPA
STRING
Knowledge Graph
Related Hypotheses (7)
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.59
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
Aquaporin-4 Polarization Rescue
Score: 0.51
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.44
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35
Show 2 more
Related Analyses (10)
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
Show 5 more
Related Experiments (6)
CSF Dynamic Biomarkers for Differential Diagnosis of NPH vs
clinical · proposed · Score: 0.90
s:** - Test tau spreading in AQP4 knockout vs wild-type mice
falsification · proposed · Score: 0.40
CSF Dynamic Biomarkers for Differential Diagnosis of NPH vs
clinical · proposed · Score: 0.40
NPH Glymphatic System Interaction Experiment
clinical · proposed · Score: 0.40
Proposed experiment from debate on Perivascular spaces and g
falsification · proposed · Score: 0.40
Experimental: CAAR-T Cell Therapy for Autoantibody-Mediated
clinical · proposed · Score: 0.40
Show 1 more
See Also (15)
Neurodegeneration
disease · KG edge: implicated_in
Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses
WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 3 hypotheses
vip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 3 hypotheses
VEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 3 hypotheses
Vagus Nerve Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses
Ubiquitin-Proteasome System Dysfunction in Neurodegener
mechanism · Pages share 3 hypotheses
ubiquitin-proteasome-dysfunction-neurodegeneration
mechanism · Pages share 3 hypotheses
Transdiagnostic Proteomic Changes in Neurodegeneration
mechanism · Pages share 3 hypotheses
Transdiagnostic Proteomic Changes in Neurodegeneration
mechanism · Pages share 3 hypotheses
Therapeutic Targets in Neurodegeneration
mechanism · Pages share 3 hypotheses
Tertiary Lymphoid Organs in Neurodegeneration
mechanism · Pages share 3 hypotheses
T-Cell Dysfunction in Neurodegeneration
mechanism · Pages share 3 hypotheses
Synthetic Lethality and PARP Inhibition in Neurodegener
mechanism · Pages share 3 hypotheses
synaptic-vesicle-cycling-neurodegeneration
mechanism · Pages share 3 hypotheses
Show 10 more