| Gene Symbol | CASRPROTEIN |
| Full Name | Calcium-Sensing Receptor Protein |
| Protein Family | C family (Class C GPCR), Metabotrophic glutamate receptor family |
| Protein Type | Receptor |
| Function | is a class C G protein-coupled receptor (GPCR) that functions as the principal molecular sensor of extracellular calcium concentrations in the body. |
| Primary Expression | Brain (hippocampus, cerebellum, cortex, substantia nigra), parathyroid, kidney, pancreas |
| Subcellular Localization | Plasma membrane, endoplasmic reticulum, synaptic terminals |
| Molecular Weight | 120 kDa (monomer), functional dimers ~240 kDa |
| UniProt ID | Q9UII2 |
| GeneCards | CASRPROTEIN |
| Human Protein Atlas | CASRPROTEIN |
| Protein Name | Calcium-Sensing Receptor Protein |
| Gene | CASR |
| PDB IDs | 5K5J, 5FBK, 5ARG, 6A2E |
| Associated Diseases | Parkinson'S Disease |
| KG Connections | 29 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |