| Gene Symbol | CCM2 |
| Full Name | Cerebral Cavernous Malformation 2 |
| Aliases | CCM2PROTEIN |
| Chromosome | 7p13 |
| Protein Type | Scaffold Protein |
| Function | encodes an essential scaffold protein that plays a critical role in vascular development, endothelial cell function, and blood-brain barrier integrity. |
| Primary Expression | endothelial cells (arterial, venous, and capillary), brain (cortex, hippocampus, cerebellum), heart (myocardium and vasculature), and lung (pulmonary |
| Subcellular Localization | and protein interactions [@glineur2019] |
| Molecular Weight | 52 kDa |
| Amino Acids | 444 aa |
| Exons | 10 |
| Pathways | TGF-β, MAPK |
| UniProt ID | [Q9BSQ5](https://www.uniprot.org/uniprot/Q9BSQ5) |
| Ensembl ID | ENSG00000168781 |
| GeneCards | CCM2 |
| Human Protein Atlas | CCM2 |
| Associated Diseases | Alzheimer's disease, Stroke |
| Databases | GeneCardsNCBI GeneHPASTRING |