protein 755 words KG: CHRM2PROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

Muscarinic Acetylcholine Receptor M2 (CHRM2)

🔬 Protein Info
Gene SymbolCHRM2
Full NameMuscarinic Acetylcholine Receptor M2
AliasesCHRM2PROTEIN
Protein TypeReceptor
FunctionThe Muscarinic Acetylcholine Receptor M2 (CHRM2) is a G protein-coupled receptor (GPCR) that mediates the effects of acetylcholine on slow inhibitory postsynaptic potentials in the heart, smooth muscl
Primary Expressionthe hippocampus, cerebral cortex, and basal ganglia, where it modulates learning, memory, and r
Ensembl IDENSG00000131617
GeneCardsCHRM2
Human Protein AtlasCHRM2
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (8)

TREM2-mediated microglial tau clearance enhancement
Score: 0.80
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.78
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69

Related Analyses (10)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (1)

Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (2)

TREM2 Protein (Triggering Receptor Expressed on Myeloid
entity · KG edge: associated_with
Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (1 edges)

CHRM2PROTEIN associated_with TREM2

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