| Gene Symbol | FXR |
| Aliases | Farnesoid X Receptor |
| Function | FXR (Farnesoid X Receptor, also known as NR1H4) is a nuclear receptor that functions as the primary sensor of bile acids in the body[@makishima1999]. |
| Pathways | NF-κB |
| GeneCards | FXR |
| Human Protein Atlas | FXR |
| Isoform | Amino Acids |
| FXRα1 | 472 |
| FXRα2 | 435 |
| FXRβ | 458 |
| FXRγ | 418 |
| Gene Variant | Effect |
| NR1H4 variants | Altered bile acid sensing |
| FXR expression | Modified function |
| FGF19 signaling | Metabolic changes |
| Associated Diseases | ALS |
| KG Connections | 3 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |