| Gene Symbol | HEPCIDIN |
| Aliases | HEPCIDINPROTEIN |
| Function | Hepcidin is the master regulator of systemic iron homeostasis and a key hormone that controls iron absorption, recycling, and distribution throughout the body. |
| Pathways | Reactive Oxygen Species |
| GeneCards | HEPCIDIN |
| Human Protein Atlas | HEPCIDIN |
| Iron status | High plasma iron → increased hepcidin (negative feedback) |
| Inflammation | IL-6 and other cytokines → increased hepcidin (via STAT3) |
| Hypoxia | Low oxygen → decreased hepcidin (via HIF) |
| Erythropoiesis | Active red blood cell production → decreased hepcidin |
| Interactions | FERROPORTIN, TRANSFERRIN |
| KG Connections | 16 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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