protein 900 words KG: HEPCIDINPROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

Hepcidin

🔬 Protein Info
Gene SymbolHEPCIDIN
AliasesHEPCIDINPROTEIN
FunctionHepcidin is the master regulator of systemic iron homeostasis and a key hormone that controls iron absorption, recycling, and distribution throughout the body.
PathwaysReactive Oxygen Species
GeneCardsHEPCIDIN
Human Protein AtlasHEPCIDIN
MoleculeInteraction
[Ferroportin](/proteins/ferroportin-protein)Direct binding
IL-6Induces expression
BMP6Induces expression
HFEModulates signaling
Transferrin receptor 2Complex formation
HIFRepresses expression
InteractionsTRANSFERRIN, FERROPORTIN
KG Connections16 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (14)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56

Related Analyses (6)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (14)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in