protein 1,754 words KG: KCNK18PROTEIN 2026-03-27
kind:proteinsection:proteinsstate:publishedtopic:migrainetopic:epilepsytopic:pain
Contents

KCNK18 Protein - Potassium Two Pore Domain Channel Subfamily K Member 18

🔬 Protein Info
Gene SymbolKCNK18
Full NamePotassium Two Pore Domain Channel Subfamily K Member 18 (TRESK)
AliasesTRESK
Chromosome10q26.3
Protein TypeChannel
Functionis a background potassium channel that contributes to the resting membrane potential and regulates neuronal excitability.
Subcellular Localization</strong></td><td>Cell membrane (plasma membrane)</td></tr>
Molecular Weight38 kDa
Amino Acids380 aa
Exons4
GeneCardsKCNK18
Human Protein AtlasKCNK18
Associated DiseasesEpilepsy
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (11)

Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.57
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lysosomal Calcium Channel Modulation Therapy
Score: 0.49

Related Analyses (12)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in