protein 1,754 words KG: KCNK18PROTEIN
Contents

KCNK18 Protein - Potassium Two Pore Domain Channel Subfamily K Member 18

🔬 Protein Info
Gene SymbolKCNK18
Full NamePotassium Two Pore Domain Channel Subfamily K Member 18 (TRESK)
AliasesTRESK
Chromosome10q26.3
Protein TypeChannel
Functionis a background potassium channel that contributes to the resting membrane potential and regulates neuronal excitability.
Subcellular Localization</strong></td><td>Cell membrane (plasma membrane)</td></tr>
Molecular Weight38 kDa
Amino Acids380 aa
Exons4
GeneCardsKCNK18
Human Protein AtlasKCNK18
Associated DiseasesEpilepsy
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (11)

Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.77
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62

Related Analyses (12)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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