| Gene Symbol | SCARB2 |
| Chromosome | 4q21.1 |
| Protein Family | CD36/SCARB2 family (scavenger receptor class B) |
| Primary Expression | Ubiquitous, highest in brain, liver, kidney, spleen |
| Subcellular Localization | Lysosomal membrane, late endosomes |
| Molecular Weight | ~60 kDa (unglycosylated) |
| Pathways | Autophagy, Mitochondrial Function, Mtor, Cholesterol, Alpha-Synuclein |
| UniProt ID | Q9Y5R4 |
| GeneCards | SCARB2 |
| Human Protein Atlas | SCARB2 |
| Protein Name | Lysosomal Integral Membrane Protein 2 |
| Gene Location | 4q21.1 |
| Protein Length | 478 amino acids |
| Structure | 12 transmembrane domains, type I membrane protein |
| Associated Diseases | Als, Ms, REM sleep behavior disorder, Synucleinopathy |
| Known Drugs/Compounds | Glutathione |
| Interactions | ARF1, GCLC, LIPA, SLC17A5, GNPTAB, SMPD1 |
| KG Connections | 98 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |