| Gene Symbol | MUNC181 |
| Aliases | MUNC181PROTEIN |
| Chromosome | 9q34.3 |
| Function | is a critical presynaptic protein that plays an essential role in neurotransmitter release and synaptic vesicle trafficking. |
| Molecular Weight | 66 kDa |
| Amino Acids | 594 aa |
| Exons | 20 |
| GeneCards | MUNC181 |
| Human Protein Atlas | MUNC181 |
| Syntaxin-1 (STX1A) | Direct binding |
| SNAP-25 | Indirect |
| Synaptobrevin-2 (VAMP2) | Indirect |
| Munc13-1 | Cooperative |
| RIM1α | Cooperative |
| Synaptotagmin-1 | Competitive |
| Associated Diseases | ALS, neurodegeneration |
| Interactions | SYNGAP1, DNAJC5, ERK, AND, SNAP-25, HSC70 |
| KG Connections | 36 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |