Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about OXPC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | OXPC |
| Linked Hypotheses | 2 hypotheses |
Knowledge base pages for this entity
graph TD
OXPC["OXPC"]
OXPC -->|"causes"| SEPSOCS["SEPSOCS"]
OXPC -->|"causes"| PFEN1["PFEN1"]
OXPC -->|"causes"| neurons["neurons"]
OXPC -->|"causes"| oligodendrocytes["oligodendrocytes"]
OXPC -->|"activates"| PRDX2["PRDX2"]
OXPC -->|"causes"| SCFD1["SCFD1"]
OXPC -->|"activates"| MEF2A["MEF2A"]
OXPC -->|"activates"| USF1["USF1"]
GRPRPROTEIN["GRPRPROTEIN"] -->|"binds"| OXPC
MUNC181PROTEIN["MUNC181PROTEIN"] -->|"binds"| OXPC| Target | Relation | Type | Str |
|---|---|---|---|
| Neurodegeneration | causes | process | 0.95 |
| SEPSOCS | causes | disease | 0.90 |
| Neurons | mediates | cell_type | 0.90 |
| Oligodendrocytes | mediates | cell_type | 0.90 |
| PFEN1 | causes | gene | 0.80 |
| PRDX2 | activates | protein | 0.80 |
| neurons | causes | cell_type | 0.80 |
| oligodendrocytes | causes | cell_type | 0.80 |
| Multiple Sclerosis | biomarker_for | disease | 0.80 |
| SCFD1 | causes | protein | 0.70 |
| TUBA4APROTEIN | causes | protein | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Microglia | modulates | cell_type | 0.90 |
| TREM2 | involved_in | gene | 0.85 |
| Oxidative Stress | causes | process | 0.85 |
| DCTN5 | associated_with | gene | 0.80 |
| GRPRPROTEIN | binds | receptor | 0.80 |
| UNC13B | associated_with | gene | 0.80 |
| MUNC181PROTEIN | binds | protein | 0.80 |
| ERLIN1 | associated_with | gene | 0.80 |
| PARP3 | associated_with | gene | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| TREM2-SYK Signaling Axis Couples OxPC Recognition to Phagocy | 0.505 | neuroinflammation | What molecular mechanisms enable microgl |
| Complement Cascade Activation Bridges Microglial OxPC Sensin | 0.452 | neuroinflammation | What molecular mechanisms enable microgl |
Scientific analyses that reference this entity
neuroinflammation | 2026-04-13 | 2 hypotheses Top: 0.505
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||