protein 1,270 words KG: NADKPROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

NAD Kinase Protein

🔬 Protein Info
Gene SymbolNADK
Full NameNAD Kinase
Chromosome1p31.3
Protein TypeKinase
FunctionNADK encodes NAD kinase, the enzyme that catalyzes NADP+ biosynthesis from NAD+.
PathwaysMapk, Immune Response
UniProt IDSearch UniProt
Ensembl IDENSG00000008130
GeneCardsNADK
Human Protein AtlasNADK
Associated Diseasesneurodegeneration
InteractionsINPP5D, RIPK1, CYTOKINES, PROINFLAMMATORY CYTOKINES
KG Connections7 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (7)

Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
APOE-Dependent Autophagy Restoration
Score: 0.61
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.51
Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration
Score: 0.45

Related Analyses (8)

Metabolomic signatures of neurodegeneration and energy metab
neurodegeneration · failed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (14)

Sirtuin Pathway Dysfunction Validation in Parkinson's Diseas
clinical · proposed · Score: 0.40
NAD depletion effects on monocyte/macrophage differentiation
exploratory · proposed · Score: 0.90
Germfree mouse colonocyte energy metabolism analysis
validation · proposed · Score: 0.90
FK866 treatment in DSS-induced colitis mouse model
validation · proposed · Score: 0.90
FK866 in azoxymethane/DSS colitis-associated cancer model
validation · proposed · Score: 0.85

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in