INPP5D

Understanding Entity Pages

This page aggregates everything SciDEX knows about INPP5D: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

INPP5D is a gene implicated in neurodegeneration research. Key relationships include: activates, associated with, implicated in. Associated with Als, Alzheimer, Ms. Connected to 25 entities in the SciDEX knowledge graph.

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graph TD
    INPP5D["<b>INPP5D</b>"]
    Alzheimer{"Alzheimer"}
    INPP5D -->|"activates"| Alzheimer
    Neurodegeneration{"Neurodegeneration"}
    INPP5D -->|"activates"| Neurodegeneration
    Als{"Als"}
    INPP5D -->|"activates"| Als
    Ms{"Ms"}
    INPP5D -->|"activates"| Ms
    APOE["APOE"]
    INPP5D -->|"activates"| APOE
    CYTOKINES["CYTOKINES"]
    INPP5D -->|"activates"| CYTOKINES
    PROINFLAMMATORY_CYTOKINES["PROINFLAMMATORY CYTOKINES"]
    INPP5D -->|"activates"| PROINFLAMMATORY_CYTOKINES
    RIPK1["RIPK1"]
    INPP5D -->|"activates"| RIPK1
    Mapk(["Mapk"])
    INPP5D -->|"activates"| Mapk
    Immune_Response(["Immune Response"])
    INPP5D -->|"activates"| Immune_Response
    neurodegeneration["neurodegeneration"]
    INPP5D -->|"implicated in"| neurodegeneration
    APP["APP"]
    APP -->|"associated with"| INPP5D
    GENES["GENES"]
    GENES -->|"activates"| INPP5D
    LGALS3["LGALS3"]
    LGALS3 -->|"activates"| INPP5D
    APOE4["APOE4"]
    APOE4 -->|"activates"| INPP5D
    NADK["NADK"]
    NADK -->|"activates"| INPP5D
    style INPP5D fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0