Contents

NFE2L3 Protein

🔬 Protein Info

Gene Symbol	NFE2L3
Full Name	Nuclear Factor Erythroid 2 Like 3
Chromosome	7p15.2
Protein Type	Transcription Factor
Function	These complexes bind to Antioxidant Response Elements (ARE sequences, 5'-TGACnnnGC-3') in the promoter regions of target genes[@sykiotis2010].
Primary Expression	various brain regions, including:
Subcellular Localization	Basic leucine zipper (bZIP) domain: Mediates DNA binding and heterodimerization with small Maf proteins ([MAFF](/pro
Molecular Weight	90 kDa
UniProt ID	[Q9Y5U8](https://www.uniprot.org/uniprot/Q9Y5U8)
Ensembl ID	ENSG00000150347
OMIM	607917
GeneCards	NFE2L3
Human Protein Atlas	NFE2L3
N-terminal Neh2-like domain	Contains regulatory elements that control protein stability and subcellular localization
Basic leucine zipper (bZIP) domain	Mediates DNA binding and heterodimerization with small Maf proteins (MAFF, MAFG, MAFK)
Associated Diseases	Ovarian Cancer
KG Connections	14 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Knowledge Graph