Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SIGLEC11: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Immune Cell Distribution | regulates | process | 0.78 |
| SORL1 | implicated_in | gene | 0.60 |
| SPI1 | implicated_in | gene | 0.60 |
| TMEM106B | implicated_in | gene | 0.60 |
| TREM2 | implicated_in | gene | 0.60 |
| SLC24A4 | associated_with | gene | 0.60 |
| SPINT1 | associated_with | gene | 0.60 |
| schizophrenia | interacts_with | disease | 0.60 |
| neurodegeneration | interacts_with | disease | 0.60 |
| XPR1 | associated_with | gene | 0.60 |
| Alzheimer's disease | interacts_with | disease | 0.60 |
| autism spectrum disorder | interacts_with | disease | 0.60 |
| microglia | expressed_in | cell_type | 0.55 |
| benchmark_ot_ad_answer_key:SIGLEC11 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ABCA1 | implicated_in | gene | 0.60 |
| ABI3 | implicated_in | gene | 0.60 |
| ACE | implicated_in | gene | 0.60 |
| ADAM17 | implicated_in | gene | 0.60 |
| APOE | implicated_in | gene | 0.60 |
| APP | implicated_in | gene | 0.60 |
| BIN1 | implicated_in | gene | 0.60 |
| CD2AP | implicated_in | gene | 0.60 |
| CD33 | implicated_in | gene | 0.60 |
| CLU | implicated_in | gene | 0.60 |
| CR1 | implicated_in | gene | 0.60 |
| CTSB | implicated_in | gene | 0.60 |
| CTSH | implicated_in | gene | 0.60 |
| EED | implicated_in | gene | 0.60 |
| GRN | implicated_in | gene | 0.60 |
| INPP5D | implicated_in | gene | 0.60 |
| LILRB2 | implicated_in | gene | 0.60 |
| PICALM | implicated_in | gene | 0.60 |
| PLCG2 | implicated_in | gene | 0.60 |
| PSEN1 | implicated_in | gene | 0.60 |
| PTK2B | implicated_in | gene | 0.60 |
| ADRA2A | associated_with | gene | 0.60 |
| CD36 | associated_with | gene | 0.60 |
| MAP1A | associated_with | gene | 0.60 |
| NFE2L3 | associated_with | gene | 0.60 |
| CDC42EP3 | associated_with | gene | 0.60 |
| FGFRL1 | associated_with | gene | 0.60 |
| MYL9 | associated_with | gene | 0.60 |
| CD33 | interacts_with | gene | 0.60 |
| MAG | interacts_with | gene | 0.60 |
| GRAMD1B | associated_with | gene | 0.60 |
| benchmark_ot_ad_answer_key:SIGLEC11 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||