protein 819 words KG: NT3PROTEIN
Contents

Neurotrophin-3 (NT-3)

🔬 Protein Info
Gene SymbolNT3
Full NameNeurotrophin 3
AliasesNT3PROTEIN
Chromosome12p13.31
Protein FamilyNeurotrophin
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionthe developing and adult CNS: - Hippocampus: Highest expression in dentate gyrus and CA3 region - Cerebral cortex
Amino Acids119 aa
PathwaysPI3K, mTOR, mtor, MAPK
UniProt ID[P20783](https://www.uniprot.org/uniprot/P20783)
Ensembl IDENSG00000185652
GeneCardsNT3
Human Protein AtlasNT3
Signal peptideTargets the protein for secretion
Pro-domainInvolved in protein folding and trafficking
Associated Diseasesneurodegeneration
InteractionsALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AMYLOID-BETA, AND, APP
KG Connections25 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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