protein 1,099 words KG: RAD50PROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

RAD50 Protein

🔬 Protein Info
Gene SymbolRAD50
Full NameDNA Repair Protein RAD50
Chromosome5q23.2
Protein FamilySMC family (Structural Maintenance of Chromosomes)
Functionencodes a crucial DNA repair protein that serves as the structural scaffold of the MRN complex (MRE11-RAD50-NBS1), which is essential for recognizing and repairing DNA double-strand breaks (DSBs).
Subcellular LocalizationNucleus (chromatin-associated)
Molecular Weight180 kDa
Amino Acids1586 aa
Gene TypeProtein coding
UniProt IDQ9XQB3
NCBI Gene ID10111
Ensembl IDENSG00000113522
OMIM604040
GeneCardsRAD50
Human Protein AtlasRAD50
Associated Diseasesneurodegeneration
InteractionsRAD52, DRP1
KG Connections3 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph